Where we get to see some of the events going on now and coming up in the Marvel Universe. (See below for a breakdown.)
We see a new group of Young Avengers.
Doyle Dormammu taking out his dad, we saw some of this in Strange Academy #13
A new Spider-man, who we know is Ben Reilly, going on in the pages of Amazing Spiderman.
A new Iron Fist. Who is heavily speculated to be (and most likely is) Swordmaster who first appeared in New Agents of Atlas #2
The return of Jack of Hearts.
And possibly the Thunderbolts coming to reclaim their name (my best guess).